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Heart Care Specialty Update

October 2014

Enrollment for Leadless Pacemaker Clinical Trial

A new clinical trial of the Nanostim™ leadless pacemaker (St. Jude Medical, Inc., St. Paul, MN) is now enrolling at University of Minnesota Heart Care. The site investigators are Quan Pham, MD, and Demosthenes Iskos, MD. The device is being tested for safety and efficacy in an international, multicenter clinical trial called LEADLESS II, which is planning to enroll 670 patients at 50 centers worldwide.

For more, visit umnhealth.org/heartcare.


New atrial fibrillation study published

Lin Y. Chen, MD, and colleagues have recently published a study clarifying the relationship between AF and cognitive decline. The study was published on July 22, 2014 in the journal Stroke.

The authors found that the presence of subclinical cerebral infarcts (SCIs) seen on MRI in patients with incident AF without stroke was associated with cognitive decline, while similar patients without SCIs did not experience the decline. Dr. Chen’s study provides new support for the use of anticoagulation therapy to prevent cognitive decline in patients with incident AF.

Chen LY, et al. Atrial Fibrillation and Cognitive Decline-The Role of Subclinical Cerebral Infarcts: The Atherosclerosis Risk in Communities Study. Stroke. 2014 Jul 22. pii: STROKEAHA.114.005243.


Successful pacemaker treatment of symptomatic AV block caused by a vagus nerve stimulator in a seizure patient published

Huagui Li, MD, PhD, and his colleagues have recently published a report in the journal Heart Rhythm (Lin Y, Li J, Li H. Heart Rhythm; published online, May 21, 2014).

A patient with drug- refractory seizure disorder developed symptomatic AV block from the vagus nerve stimulator that was quite effective to control her seizure. She presented to Fairview Southdale Hospital after years of unsuccessful treatment of her symptoms. After her problem was correctly diagnosed her symptoms were successfully treated with an implantable pacemaker.

In the past, many seizure patients had to abandon the vagus nerve stimulator therapy because of the vagus nerve stimulation-induced bradycardia. This report may help many other seizure patients to continue the vagus nerve stimulator therapy even if they have vagus nerve stimulation-induced bradycardia as long as the patients are implanted with pacemakers.

Related Articles

October 2014

Leading Edge, Minimally Invasive Procedures for Cardiac Arrhythmias

The minimally invasive LARIAT™ procedure eliminates the main source of AF-related stroke without open heart surgery, while avoiding potentially serious side effects associated with blood-thinning medication.

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October 2014

AF Management in a Patient Intolerant to Oral Anticoagulation Therapy

The case of an elderly gentleman with atrial fibrillation in the setting of a complex cardiac history who was intolerant to oral anticoagulation therapy. He was successfully managed using the LARIAT™ procedure.

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October 2014

Targeted Radiofrequency Ablation to Manage Electrical Storm

Here we describe a patient with a complex cardiac history and VT electrical storm that was successfully managed using highly targeted radiofrequency ablation.

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