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Pediatric Specialty Updates

June 2017

Diabetes specialist joins M Health team

Megan Oberle, MD, will join the University of Minnesota Health pediatric endocrinology team on July 31, 2017, following the completion of a fellowship in endocrinology at Children’s Hospital of Philadelphia. Oberle has a clinical interest in food insecurity and obesity.

Clinical trials test approaches to T1D prevention

National Institutes of Health clinical trials investigating therapies designed to prevent the advance of type 1 diabetes to clinical stage are available through University of Minnesota Health clinicians. Individuals identified as at-risk for diabetes may be eligible to participant and receive antigen therapy (oral insulin) or immunologic therapy (abatacept, anti-CD3). Three new studies investigating separate drug regimens (abatacept+rituximab, hydroxychloroquine, or aldomet) will be available for enrollment by fall 2017, and a separate study testing a vaccine incorporating multiple peptides of proinsulin and IA-2 will be available by early 2018. University of Minnesota Health clinicians Antoinette Moran, MD, Brandon Nathan, MD, Muna Sunni, MBBCh, and Jennifer McVean, MD, are leading these trials. For information, contact coordinator Beth Pappenfus: papp0086@umn.edu.

In a study of children and adolescents, Nathan is also evaluating the efficacy and safety of a new insulin that works faster than any currently available on the market.

M Health physicians train the trainers in Africa

The University of Minnesota Health pediatric endocrinology team is improving diabetes care in Africa. For several years, Antoinette Moran, MD, and M Health physicians, nurses and dietitians along with University of Minnesota Medical School fellows and students have traveled to Uganda to teach physicians, nurses, and dietitians the interdisciplinary care model critical to T1D care. In 2007, no pediatric endocrinologists were established in the African continent outside of the country of South Africa. Today, as a result of the fellowship program started in Nairobi in 2009, there are 3 in Uganda alone and more than 70 throughout Africa. Diagnoses in Ugandan children have gone from approximately 100 known cases in 2007 to approximately 1,000 in 2016 now that more children are surviving.

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